Blue Eyes

Blue eyes can be on humans too.
Blue eyes are rare in mammals; one example is the quite recently discovered marsupial, the Blue-eyed Spotted Cuscus (Spilocuscus wilsoni). The trait is hitherto known only from a single primate other than humans – Sclater's Lemur (Eulemur flavifrons) of Madagascar. While some cats and dogs have blue eyes, this is usually due to another mutation that is associated with deafness. But in cats alone, there are four identified gene mutations that produce blue eyes, some of which are associated with congenital neurological disorders. The mutation found in the Siamese cats is associated with strabismus (crossed eyes). The mutation found in blue-eyed solid white cats (where the coat color is caused by the gene for "epistatic white") is associated with deafness. However, there are phenotypically identical, but genotypically different, blue-eyed white cats (where the coat color is caused by the gene for white spotting) where the coat color is not strongly associated with deafness. In the blue-eyed Ojos Azules breed, there may be other neurological defects. Blue-eyed non-white cats of unknown genotype also occur at random in the cat population